| Amazon Linux 2023 | All versions | Yes | 4KB | AMIs | Yes | Pointer Authentication enabled on Graviton3 |
| Amazon Linux 2 | 2.26-35 or later | Yes | 4KB | AMIs | Yes | End of Life (EOL) scheduled 2025-06-30 |
| Ubuntu Pro | 22.04 LTS | Yes | 4KB | MarketPlace | Yes | |
| Ubuntu | 24.04 LTS | Yes | 4KB | noble | Yes | |
| Ubuntu | 22.04 LTS | Yes | 4KB | jammy | Yes | |
| Ubuntu | 20.04 LTS | Yes | 4KB | focal | Yes | |
| Ubuntu | 18.04 LTS | Yes (*) | 4KB | bionic | Yes | (*) needs apt install libc6-lse. Free support ended 2023/05/31. |
| SuSE | 15 SP2 or later | Planned | 4KB | MarketPlace | Yes | |
| Redhat Enterprise Linux | 8.2 or later | Yes | 64KB | MarketPlace | Yes | |
Redhat Enterprise Linux | 7.x | No | 64KB | MarketPlace | | Supported on A1 instances but not on Graviton2 and later based ones |
| AlmaLinux | 8.4 or later | Yes | 64KB | AMIs | Yes | |
| Alpine Linux | 3.12.7 or later | Yes (*) | 4KB | AMIs | | (*) LSE enablement checked in version 3.14 |
| CentOS | 8.2.2004 or later | No | 64KB | AMIs | Yes | |
| CentOS Stream | 8 | No (*) | 64KB (*) | Downloads | | (*) details to be confirmed once AMI's are available |
CentOS | 7.x | No | 64KB | AMIs | | Supported on A1 instances but not on Graviton2 and later based ones |
| Debian | 12 | Yes | 4KB | Community or MarketPlace | Yes | |
| Debian | 11 | Yes | 4KB | Community or MarketPlace | Yes | |
| Debian | 10 | Planned for Debian 11 | 4KB | Community or MarketPlace | Yes, as of Debian 10.7 (2020-12-07) | |
| FreeBSD | 12.1 or later | No | 4KB | Community or MarketPlace | No | Device hotplug and API shutdown don't work |
| FreeBSD | 13.0 or later | Yes | 4KB | Community or MarketPlace | No | Device hotplug and API shutdown don't work |
| FreeBSD | 14.1 or later | Yes | 4KB | Community or MarketPlace | Yes | |
| Flatcar Linux | 3033.2.0 or later | Yes | 4KB | AMIs or marketplace | Yes | |
| Rocky Linux | 8.4 or later | Yes (*) | 64KB (*) | ISOs | | Release Notes
(*) details to be confirmed once AMI's are available |